The college friends Jeff, Marcy, Paul, Karen and Bert want to spend their holidays in a solitary hut together and have only one thing in mind: celebrate and relax. Just arrived, eerie events take their course: Karen’s body has suddenly bloody bubbles, their skin starts to dissolve gradually. Disgusted and full fear block the friends of Karen in a dark shed. While the group is considering whether and how they can help Karen, them it is clear that each of them could already be infected with the contagious and deadly virus. From the fight against the disease, a battle of the friends against each other is very soon.
In the horror film cabin fever, a group of young people will be decimated by an aggressive virus.